| Sinonim |
5-methyltetrahydrofolate homocysteine methyltransferase, 5-methyltetrahydrofolate-homocysteine methyltransferase, 5-methyltetrahydrofolate-homocysteine S-methyltransferase, 5-methyltetrahydrofolate-homocysteine methyltransferase, 12-methyltetrahydrofolate-homocysteine S-methyltransferase, 5-methyltetrahydrofolate-homocysteine methyltransferase, 12-methyltetrahydrofolate-homocysteine S-methyltransferase, 6-methyltetrahydrofolate-homocysteine methyltransferase, Bt-methyltetrahydrofolate-homocysteine S-methyltransferase, 12-methyltetrahydrofolate-synthylsteine methyltransferase, Btetrahydrofolate-homocysteine dependen dependen metionin sintase, Met1p, MetH, metionin sintase, metionin sintetase, methyltetrahydrofolate-homocysteine vitamin B5 methyltransferase, methyltransferase, methyltetrahydrofolate-homocysteine, MetS, MS, MS5, MTR, N-methyltetrahydrof, methyl-homocysteine, MetS, MS, MS5, MTR, N-methyltetrahydrof, methyl-homocysteine -methyltetrahydrofolate-homocysteine cobalamin methyltransferase, N12-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase, tetrahydrofolate methyltransferase, tetrahydropteroylglutamate methyltransferase, tetrahydropteroylglutamic methyltrans, vitamin BXNUMX methyltransferase |
| komentar |
Mengandung zinc dan cobamide. Enzim menjadi tidak aktif sesekali selama siklusnya dengan mengoksidasi Co (I) menjadi Co (II). Reaktivasi dengan metilasi reduktif dikatalisis oleh enzim itu sendiri, dengan S-adenosil-L-metionin sebagai donor metil dan sistem pereduksi. Untuk enzim mamalia, sistem pereduksi melibatkan NADPH dan EC 1.16.1.8, [metionin sintase] reduktase. Pada bakteri, zat pereduksi adalah flavodoksin, dan tidak diperlukan katalis lebih lanjut (flavodoksin disimpan dalam keadaan tereduksi oleh NADPH dan EC 1.18.1.2, ferredoxin¡ªNADP + reduktase). Bertindak pada monoglutamat serta triglutamat folat, berbeda dengan EC 2.1.1.14, 5-methyltetrahydropteroyltriglutamate¡ªhomocysteine S-methyltransferase, yang hanya bekerja pada triglutamat. |
